Third-party testedMelanocortin Receptor Agonist
PT-141
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone. Laboratory research examines its non-selective agonism at melanocortin receptors, principally MC3R and MC4R, and the central-nervous-system pathways those receptors mediate. Supplied lyophilized for in-vitro and animal-model research.
About the compound
What PT-141 is.
PT-141, also called bremelanotide, is a synthetic cyclic peptide of seven amino acids derived from alpha-melanocyte-stimulating hormone. Unlike Melanotan II, which is studied mainly for pigmentation, research on PT-141 has concentrated on melanocortin receptor signalling in the central nervous system — principally MC3R and MC4R. The published work is in animal models and controlled clinical literature; nothing here is a claim about what it does in a person, and it is supplied for laboratory research only.
A melanocortin agonist, studied for central rather than peripheral effects
Specification
- Purity
- 99%+ (HPLC)
- Identity
- Confirmed by mass spectrometry
- Form
- Lyophilized powder
- Testing
- Janoshik Analytical & Kovera Labs, per batch
- Use
- In-vitro laboratory research only
Lyophilized. Store at -20 °C. Avoid repeated freeze-thaw cycles.
Compound information
- Type
- Synthetic peptide reference standard
- CAS number
- 189691-06-3
- Amino acids
- 7
- Modification
- Cyclic lactam, C-terminal amide
- Molecular formula
- C50H68N14O10
- Molecular weight
- 1,025.2 g/mol
Also known as
- Bremelanotide
- PT 141
Verify against PubChem CID 9941379 — every figure above is from that record.
PT-141 technical specificationStorage & stability
- Lyophilized−20°C
- LightLight sensitive — amber vial
- SolubilitySoluble in recon water
Reconstituted shelf life for this compound is not published. Ask us and we will confirm it for your lot.
Certificate of Analysis
99%+
Identity purity
Every lot of PT-141 is independently tested before release. Third-party verified — we never self-certify.
- Compound
- PT-141
- Method
- HPLC + Mass Spectrometry
- Testing lab
- Janoshik Analytical / Kovera Labs
- Identity — Confirmed by mass spectrometry (MS)
- Purity — Quantified by HPLC — 99%+ standard
- Net content — Verified against label claim
- Appearance — Inspected before release
COA documentation available on request — info@purechainpeps.com
Research
What PT-141 has been studied for.
A plain-language summary of the published work. Almost all of it is in cells and animals — where a study was done in people, it says so.
01
Melanocortin receptor signalling
PT-141 binds MC1R, MC3R and MC4R without strong selectivity between them. Laboratory work has focused on MC3R and MC4R, which are expressed in the central nervous system rather than in skin.
02
Central versus peripheral action
Much of the published interest is in the fact that its effects appear to originate centrally rather than through the vascular system, which distinguishes it from the mechanism of several other studied compounds.
03
Relationship to Melanotan II
It is a structural relative of Melanotan II and was identified while studying it. The two are frequently compared in the literature because their receptor profiles overlap but their studied outcomes differ.
04
Pigmentation
Because it binds MC1R, pigmentation appears in the research alongside the central findings, though it is not the primary focus of most published work.
Sold for laboratory research use only. Not a drug, not a supplement, and not for human or veterinary use. Nothing above is a claim about what this compound does in people.
Researchers also added
What PT-141 is usually ordered alongside.
Grouped by what the published research actually studies together — not by what sits in the same category.
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