Third-party testedMitochondrial Peptide
MOTS-C
MOTS-c (10mg) (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a unique mitochondrial-derived peptide. In laboratory settings, it is extensively utilized to study cellular energy metabolism, skeletal muscle regulation, and the activation pathways of AMP-activated protein kinase (AMPK).
About the compound
What MOTS-C is.
MOTS-C is encoded by the DNA inside mitochondria, which makes it unusual. Animal and cell research has examined it for effects on how cells use glucose and on exercise-related metabolism.
Coded by mitochondrial DNA, not nuclear DNA
Specification
- Purity
- 99%+ (HPLC)
- Identity
- Confirmed by mass spectrometry
- Form
- Lyophilized powder
- Testing
- Janoshik Analytical & Kovera Labs, per batch
- Use
- In-vitro laboratory research only
Lyophilized. Store at -20 °C. Avoid repeated freeze-thaw cycles.
Compound information
- Type
- Synthetic peptide reference standard
- CAS number
- 1627580-64-6
- Amino acids
- 16
- Molecular formula
- C101H152N28O22S2
- Molecular weight
- 2,174.6 g/mol
Sequence
MRWQEMGYIFYPRKLR
Also known as
- Mitochondrial ORF of the 12S rRNA type-c
Verify against PubChem CID 146675088 — every figure above is from that record.
MOTS-C technical specificationStorage & stability
- Lyophilized−20°C
- Reconstituted14–21 days refrigerated
- LightLight sensitive — amber vial
- SolubilitySoluble in bacteriostatic water
Bundle & save
Buy more, pay less per vial.
The discount applies automatically at checkout — no code to remember. Prices shown are for MOTS-C 10mg.
Save up to 17%
$52.99each
Single vial price
$5.30 per mg
- Order total
- $52.99
- You save
- —
$50.34each
$52.99 −5%
$5.03 per mg
- Order total
- $100.68
- You save
- $5.30
$48.75each
$52.99 −8%
$4.88 per mg
- Order total
- $146.25
- You save
- $12.72
$46.63each
$52.99 −12%
$4.66 per mg
- Order total
- $233.15
- You save
- $31.80
$43.98each
$52.99 −17%
$4.40 per mg
- Order total
- $439.80
- You save
- $90.10
Volume pricing is applied per size. Mixing sizes is fine — each size earns its own tier.
Certificate of Analysis
99%+
Identity purity
Every lot of MOTS-C is independently tested before release. Third-party verified — we never self-certify.
- Compound
- MOTS-C
- Method
- HPLC + Mass Spectrometry
- Testing lab
- Janoshik Analytical / Kovera Labs
- Identity — Confirmed by mass spectrometry (MS)
- Purity — Quantified by HPLC — 99%+ standard
- Net content — Verified against label claim
- Appearance — Inspected before release
COA documentation available on request — info@purechainpeps.com
Research
What MOTS-C has been studied for.
A plain-language summary of the published work. Almost all of it is in cells and animals — where a study was done in people, it says so.
01
Coded by the mitochondria themselves
MOTS-c is unusual — it is encoded in mitochondrial DNA rather than in the cell nucleus, one of a small number of peptides known to work that way.
02
Metabolic regulation
Mouse studies have investigated its effect on insulin sensitivity and glucose handling, particularly in muscle tissue.
03
Exercise and stress response
Research has measured how MOTS-c levels change with physical stress, and looked at the AMPK pathway as the proposed mechanism.
04
Ageing research
Levels have been observed to decline with age in several models.
Sold for laboratory research use only. Not a drug, not a supplement, and not for human or veterinary use. Nothing above is a claim about what this compound does in people.
Researchers also added
What MOTS-C is usually ordered alongside.
Grouped by what the published research actually studies together — not by what sits in the same category.

NAD+
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The pairing that dominates mitochondrial-energy research.
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SS-31
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Glutathione
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Shared interest in oxidative-stress models.
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Bacteriostatic Water
from$9.99
Every lyophilised vial has to be reconstituted before anything can be done with it.
View compound
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